6
Charles Barkley
Charles Barkley
Christian Petersen/Getty Images
The former professional basketball star said he’s lost around 60 pounds by taking the GLP-1 Mounjaro, in addition to maintaining a healthy diet and exercise. “It's been great, I'm starting to feel like a human being.” Barkley candidly revealed on The Pat McAfee Show, per a Twitter (now X) post. Describing his experience, he said, “It's been amazing,” and added that his ultimate goal is to live longer. On the show, he also explained he gained a lot of the initial weight when he got his new hips, and now he’s seeing the weight come off. “I started at 352, and I’m down to 290,” he said, now with an ultimate goal of 270, according to Yahoo News.

7
Claudia Oshry
Claudia Oshry
Evan Agostini/AP Photo
For Oshry, a comedian, co-host of the podcast The Toast, and creator of the popular Instagram account @girlwithnojob, taking a GLP-1 was a no-brainer. She told listeners on her podcast, “You thought they were going to make a weight loss drug and I wasn't going to take it?” She later went on to say, “You're dumb. Of course, I'm f***ing taking it,” according to People. At first, it wasn’t so easy for Oshry to discuss using the medication — she didn’t feel comfortable admitting she was on it. Now, she’s candidly talking about going off the drug, and sharing her new struggles. “I'm so hungry all the mother-f***ing time and I'm always looking for good treats cause I'm still trying to lose weight but on my own,” she said in a TikTok video.

8
Lauren Manzo
Lauren Manzo
Mike Pont/Getty
Manzo, the daughter of Real Housewives of New Jersey alumni Caroline Manzo, announced she lost 50 pounds from following a gluten- and dairy-free diet, and another 30 pounds by taking Mounjaro, as People reported. Manzo was motivated to lose weight because her weight of 280 pounds took a toll on her mental health. At first, Manzo received public pushback, but, as she explained on Page Six’s Virtual Reali-Tea, “I get it — people don't like it, people don't applaud it, people aren't whatever, but it's a shot in your stomach once a week, it's the same as Ozempic. ... You guys have seen the struggle with this since I'm 20 years old, and it's been really hard for me.”

9
Elon Musk
Elon Musk
Lisa O'Connor/Getty Images
When one fan asked the Tesla and SpaceX entrepreneur in October 2022 on X, “What’s your secret? You look awesome, fit, ripped, and healthy. Lifting weights? Eating healthy?” Musk replied “Fasting,” “And Wegovy,” according to Business Insider. Per the Economic Times, Musk also shared that he’s down 30 pounds, and in addition to fasting and Wegovy, his other strategy is “no tasty food near me.” When Musk first made his announcement, it caused a spiral of press for GLP-1 weight loss and diabetes , as Musk was one of the first celebrities to speak openly about using the medication, according to the University of Colorado Anschutz Medical Campus.

10
Rosie O’Donnell
Rosie ODonnell
Monica Schipper/Getty
The actor and comedian first revealed on TikTok that she shed 10 pounds on Mounjaro, and then followed it up with another post that she lost 15 pounds on the lowest dose, notes Newsweek. Although her weight loss stagnated, O’Donnell’s doctor told her that what matters is that her A1C is going down. (As the Cleveland Clinic notes, A1C is a measurement of the average of your blood sugar levels over the past three months.). She has since been on Mounjaro for one year, per an Instagram post.